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Course Descriptions

Web Catalog Information Subject to Change

The web version of the ESF Catalog is updated as needed throughout the year. To view the version officially associated with a particular date of entry to the College, please refer to the appropriate catalog of record.

Course Descriptions

BPE

BPE 132 Orientation Seminar: Bioprocess Engineering (1)
One hour lecture per week or three-hour lab/field trip per week. Introduction to campus resources available to ensure academic success. Introduction to bioprocess engineering as a field of inquiry and career path. Fall.
Note: Credit will not be granted for both BPE 132 and PSE 132.

BPE 230 China Experience (3)
Forty five hours (equivalent) of lecture and field studies. General survey of the history of China from ancient societies through the current time, with attention to cultural, ecological and natural resource issues focused on selected localities of China. The locality and/or hot spots will be selected from: the invention of paper; printing technology; renewable energy; anaerobic digesion of manual / plant biomass; wastewater treatment; Great Walls; Forbidden City; Three Gorges area; Canals; Chinese gardens; Sichuan; Dujianyang Irrigation Dam/Channels; Panda preservation; Hakka culture; Tibetan culture; plants and vegetation, etc. Analysis of the evolution of the Chinese culture. Historical and contemporary influences of China. Spring, Fall or Summer.

BPE 296 Special Topics in Engineering (1 - 3)
Provides experimental, interdisciplinary, or special coursework at the freshman and sophomore levels within the field of environmental resources engineering. Subject matter and course format vary from semester to semester and section to section. Fall and Spring.

BPE 300 Introduction to Industrial Bioprocessing (3)
Three hours of lecture and discussions. Industrial examples of biotechnology and bioprocessing will be reviewed. Topics include applications of biotechnology and bioprocessing to the food, water and wastewater treatment, industrial biotechnology, biopharmaceutical, biochemical and biofuel industries. Through case studies of process flow sheets for different products students will develop an understanding of unit operations typically utilized in bioprocessing manufacturing operations. Fall.
Prerequisite(s): EFB 103 and EFB 104; co-requisite(s): FCH 221 and FCH 222.

BPE 304 Summer Internship in Bioprocess Engineering (2)
Twelve weeks full time bioprocessing employment approved by the Department between the junior and senior years. The student must submit a comprehensive report and give a presentation to fulfill this requirement. Summer.
Prerequisite: PSE 370 or equivalent.

BPE 305 Co-op Experience in Bioprocess Engineering (2)
One semester full-time bioprocessing experience as an engineering intern on company-assigned projects. Typically, the student works for a semester and adjacent summer also taking BPE 304. The student must submit a comprehensive report and give a presentation to fulfill this requirement. Fall and Spring.
Prerequisite: PSE 370 or equivalent.

BPE 310 Colloid and Interface Science (3)
Three hours of lecture per week. This course will cover the basic principles of colloidal and interfacial science as applied to bioprocesses. It will provide a foundation and theoretical understanding that will be applied in bioseparations, transport phenomena, biochemical/bioprocess engineering and other advanced courses in the bioprocess engineering curriculum. Fall.
Prerequisites: PSE 370, PSE 361, FCH 150, FCH 152. Note: Credit will not be granted for both BPE 310 and PSE 467.

BPE 335 Transport Phenomena (3)
Three hours of lecture per week. Principles of heat and mass transfer as applied to the bioprocess industries. Topics include conduction, convective heat and mass transfer, diffusion of both steady-state and transient situations, analogies for heat and mass transfer, boundary layers, porous media transport, heat and mass transfer analyses. Discussion of specific bioprocess examples. Spring.
Prerequisites: PSE 370, PSE 371. Note: Credit will not be granted for both BPE 335 and ERE 534.

BPE 336 Transport Phenomena Laboratory (1)
Three hours of laboratory per week. Introduction to report writing and laboratory safety. Experiments on fluid mechanics, heat transfer, diffusion, and convective mass transfer as applied to the bioprocess industries. Data analysis and data presentation in oral and written form are required. Spring.
Prerequisites: PSE 370 and PSE 371 or equivalents. Co-requisite: BPE 335 (or prerequisite).

BPE 420 Bioseparations (3)
Three hours of lecture per week. Major unit operations used for the separation, purification and recovery of products from complex mixtures. Separation processes including sedimentation, filtration, centrifugation, membrane ultra-filtration, nanofiltration, ion exchange processes, chromatographic separations. Fall.
Prerequisite: BPE 310. Note: Credit will not be granted for both BPE 420 and BPE 620.

BPE 421 Bioprocess Kinetics and Systems Engineering (3)
Three hours of lecture per week. Topics in biochemical kinetics and reaction engineering are discussed including their application to microbiological systems used for bioprocessing. Batch and continuous biochemical reactor designs. The role of agitation in gas and solids delivery and heat removal for inclusion in design decisions. Impact of engineering parameters and design decisions on operability and economics. Fall.
Prerequisite: BPE 335. Co-requisite: BPE 420. Note: Credit will not be granted for both BPE 421 and BPE 621.

BPE 435 Unit Process Operations (3)
Two hours of lecture and three hours of laboratory and/or recitation, discussions per week. Topics include packed towers, tray columns, fluidized bed, fluid mechanic limitations, pressure drop, mass transfer coefficient, mass transfer limits, thermodynamic limits, equilibrium stage calculations, packed tower and tray column design and performance analysis. Fall.
Prerequisite(s): BPE 335/336.

BPE 438 Introduction to Biorefinery Processes (3)
Three hours of lecture and discussions per week. Topics covered include chemical and physical properties of biomass feedstocks; sustainable biomass production/utilization, chemical and biological processes of converting plant biomass to chemicals, liquid fuels, and materials. Focus on green chemistry and/or environmentally benign processes, with some discussions on political and social aspects of sustainability and renewability. Fall.
Prerequisite(s): Cell biology and BPE 335 Transport Phenomena. Note: Credit will not be granted for both BPE 438 and BPE 638.

BPE 440 Bioprocess and Systems Laboratory (3)
One hour of lecture and six hours of laboratory per week. Measurement and analysis of bioprocess systems, including steady-state and dynamic modeling of systems. Investigation of various bioprocesses including fermentation, enzymatic reactions, and reactive processes involving lignocellulosic materials. Spring.
Prerequisite: BPE 420 and BPE 421.

BPE 441 Biomass Energy (3)
Three hours of lecture per week. Historical, current and future uses of biomass as a source of renewable energy for the production of bioenergy, biofuels and bioproducts. Characteristics of biomass, their conversion to different forms of energy and end products, and an assessment of their sustainability. Spring.
Prerequisite: ESC 325, ESC 335 or permission of instructor; one semester of freshman chemistry or permission of instructor. Note: Credit will not be granted for both BPE 441 and BPE 641.

BPE 481 Bioprocess Engineering Design (3)
2.5 hours of lecture and 1.5 hours of studio per week. Design project and procedure; open-ended design options; mass/energy balances; unit operations; safety considerations; and economic analysis. Process simulation and computer-aided design for process synthesis and plant layout. Formulation and solution of original design problem(s) under realistic (e.g., socioeconomic, process, environmental, safety) constraints. Spring.
Prerequisites: PSE 480, BPE 420, BPE 421, BPE 435, or equivalents. Note: Credit will not be granted for both BPE 481 and BPE 681.

BPE 496 Special Topics (1 - 3)
Lectures, readings, problems and discussions. Topics in environmental or resource engineering as announced. Fall and/or Spring.

BPE 498 Research Problem in Bioprocess Engineering (1 - 4)
Independent study. The student is assigned a research problem in bioprocess engineering. The student must make a systematic survey of available literature on the assigned problem. Emphasis is on application of correct research techniques rather than on discovery of results of commercial importance. The information obtained in the literature survey, along with the data developed as a result of the investigation, is to be presented as a technical report. Fall, Spring, and Summer.

BPE 501 Bioprocess Microbiology (3)
Two hours of lecture and three hours of laboratory/discussion per week. Topics include general microbiology, enzymology, enzyme kinetics, biochemistry, metabolic regulation, microbial growth and product formation (with general stoichiometry), media formulation and bioprocess design including batch, fed-batch, and continuous modes, techniques for product recovery and purification, and mammalian cell lines/culture. Microbiological growth media, batching, and the operation of bench-top bioreactors and various analytical instrumentation. Fall.
Prerequisites: Permission of instructor; basic understanding of chemistry and biology; appropriate quantitative skills.

BPE 503 Bioprocess Plant Design (3)
Three hours of lecture per week. Topics covered include integration of process and support systems and equipment; concepts of facility design integrating Good Manufacturing Practice (GMP), equipment and systems cleanability, people flow, product protection, capital investment, and operating costs. This course will focus towards facility design in the bioprocess industry. Spring.
Prerequisite(s): BPE 620, BPE 621

BPE 510 Introduction to Polymer Coatings (3)
Fundamental science of polymerization and film formation for a wide class of organic coatings, including acrylics, latexes, polyesters, amino resins, epoxies, alkyds, and silicon derivatives as well as the integration of appropriate binders and additives affecting coating quality. Reaction chemistries and their distinguishing characteristics for several cross-linking agents. Reaction kinetics are considered with emphasis on the influence of conditions during synthesis. Various organic coatings are compared based on desired mechanical and optical properties along with specific applications. The nature of defects and the resulting effect on product lifetime of coatings are examined. Online Academic Year and/or Summer Session.
Prerequisite(s): B.S. from an accredited institution with at least one semester of organic chemistry or permission of instructor.

BPE 511 Radiation Curing Equipment, Instrumentation and Safety (3)
Technologies used for commercial radiation curing for energy-efficient and environmentally-responsible curing of resins, inks, coatings and adhesives pertinent to industry chemists, engineers, technicians, and managers. Ultra violet light (UV), electron beam (EB), radio frequency (RF) and Infrared (IR) generating systems, along with ancillary equipment used to quantify energy deposition. Basic equipment functions, interaction of radiation sources with specific substrates and chemistries, benefits and drawbacks of each technology, and safety and handling considerations. Emphasis is placed on effectively selecting and justifying equipment appropriate for specific applications. Online Academic Year and/or Summer Session.
Prerequisite(s): B.S. from an accredited institution with at least one semester of organic chemistry or permission of instructor.

BPE 535 Transport Phenomena (3)
Three hours of lecture per week. Principles of heat and mass transfer as applied to the bioprocess industries. Topics include conduction, convective heat and mass transfer, diffusion of both steady-state and transient situations, analogies for heat and mass transfer, boundary layers, porous media transport, heat and mass transfer analysis. Discussion of specific bioprocess examples. Spring.
Note: Credit will not be granted for both BPE 335 and BPE 535.

BPE 536 Radiation Curing of Polymer Technologies (3)
Broad treatment of development and use of radiation curing of polymer technologies as they apply to industry-related roles such as chemists, engineers, technicians, and managers. Properties and development of free-radical and cationic systems initiated by various radiation sources. Chemical and physical underpinnings of common radiation curable materials and mechanisms. Analysis techniques that monitor the cure reaction and the properties of cured material. Emphasis on the considerations and challenges in common applications of radiation curable polymer systems and associated costs, regulatory, and safety considerations. Online Academic Year and/or Summer Session.
Prerequisite(s): B.S. from an accredited institution with at least one semester of organic chemistry or permission of instructor.

BPE 596 Special Topics (1 - 3)
Lectures, conferences, discussions and laboratory. Topics in environmental and resource engineering not covered in established courses. Designed for the beginning graduate student or selected upper-division undergraduate. Fall and/or Spring.

BPE 620 Bioseparations (3)
Three hours of lecture per week. Cell disruption, solid liquid separations, centrifugation, chromatographic techniques (gel filtration, affinity, ion exchange), and membrane processes. Extraction. Crystallization and drying. Aseptic filtration. Fall.
Prerequisite: BPE 501. Note: Credit will not be granted for both BPE 620 and BPE 420.

BPE 621 Bioreaction Engineering (3)
Three hours of lecture/discussion per week. Bioprocess kinetics, reaction engineering, mass and energy balances, stoichiometry, enzyme kinetics, growth and product synthesis kinetics, mass transfer effects, bioreactor analysis and design, instrumentation and control, batch processing, bioreactor scale-up, agitation, oxygen delivery, heat removal and kinetics of sterilization (clean and sterilization in place (CIP and SIP). Spring.
Prerequisites: Mass and Heat Transfer, or Transport Phenomena. Note: Credit will not be granted for both BPE 621 and PBE 421.

BPE 635 Unit Process Operations (3)
Two hours of lecture and three hours of laboratory and/or recitation, discussions. Topics include packed towers, tray columns, fluidized bed, fluid mechanic limitations, pressure drop, mass transfer coefficient, mass transfer limits, thermodynamic limits, equilibrium stage calculations, packed tower and tray column design and performance analysis. Fall.

BPE 638 Introduction to Biorefinery Processes (3)
Three hours of lecture and discussions per week. Topics covered include chemical and physical properties of biomass feedstocks; sustainable biomass production/utilization, chemical and biological processes of converting plant biomass to chemicals, liquid fuels, and materials. Focus on green chemistry and/or environmentally benign processes, with some discussions on political and social aspects of sustainability and renewability. Fall.
Note: Credit will not be granted for both BPE 438 and BPE 638.

BPE 640 Bioprocess Kinetics Experiments and Data Analysis (3)
One hour of lecture and six hours of laboratory per week. Planing and execution of laboratory exercises. Measurement and analysis of adsorption, chemical and biological transformations,including batch and/or continuous systems. Adsorption and chemical transformation or catalytic reactions may include solid catalyst(s), acid catalyst(s), base catalysts(s) or other agents. Biological transformtaion may include enzyme, bacteria, fungi or yeast. Bioprocess kinetics and mass transfer effects. Coaching fellow students on experimental procedures and safety requirements. Parametric analysis. Report writing and seminar presentation. Spring.
Prerequisite(s): Consent of instructor Note: Credit will not be granted for both BPE 440 and BPE 640.

BPE 641 Biomass Energy (3)
Three hours of lecture per week. Historical, current and future uses of biomass as a source of renewable energy for the production of bioenergy, biofuels and bioproducts. Characteristics of biomass, their conversion to different forms of energy and end products and an assessment of their sustainability. Spring.
Prerequisite: ESC 525, ESC 535 or permission of instructor; one semester of freshman chemistry or permission of instructor.

BPE 681 Bioprocess Plant Design (3)
Three hours of lecture per week. Topics covered include integration of process and support systems and equipment; concepts of facility design integrating Good Manufacturing Practice (GMP), equipment and systems cleanability, people flow, product protection, capital investment, and operating costs. This course will focus towards facility design in the biopharmaceutical industry. Spring.
Prerequisites: BPE 620, BPE 621 or equivalents.

BPE 796 Advanced Topics (1 - 3)
Lectures, conferences, discussions and laboratory. Advanced topics in forest engineering, paper science and engineering, and wood products engineering. Fall and/or Spring.
Prerequisite: Permission of instructor.

BPE 797 Seminar (1 - 3)
Discussion of assigned topics in the fields related to Bioprocess Engineering. Spring and Fall.

BPE 798 Research in Bioprocess Engineering (1 - 12)
Independent research topics in Bioprocess Engineering. Fall, Spring or Summer.
Credit hours to be arranged.

BPE 898 Professional Experience/Synthesis (1 - 6)
A supervised, documented professional work experience in the Master of Professional Studies degree program. Fall, Spring, or Summer.
Pre- or co-requisite(s): Approval of proposed study plan by advisor, Faculty, and any sponsoring organization.

BPE 899 Master's Thesis Research (1 - 12)
Research and independent study for the master's thesis. Fall, Spring or Summer.
Credit hours to be arranged.

BPE 999 Doctoral Thesis Research (1 - 12)
Research and independent study for the doctoral dissertation. Fall, Spring or Summer.
Credit hours to be arranged.


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