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14th Upstate New York NMR Conference and Structural Biology SymposiumOctober 19 - 20, 2015
SUNY-ESF Gateway Center
Syracuse, NY

Thanks to everyone who attended the 14th Annual Upstate New York NMR Conference and 1st Structural Biology Symposium! We look forward to seeing you next year!

The Syracuse Hill Colleges (SUNY-ESF, Syracuse University and SUNY Upstate Medical University) are inviting life science and biotechnology researchers to attend a two day event featuring the 14th Upstate NY NMR Symposium and the 1st Upstate Structural Biology Symposium, to be held October 19 & 20, 2015, at SUNY-ESF's Gateway Center.

The two day event features oral presentations and a poster session covering NMR spectroscopy related topics (on day one) and more general structural biology based themes (on day two).

The NMR symposium is also dedicated to celebrating the recent installation of the NIH funded Bruker Avance 800 MHz NMR with cryo probe at SUNY-ESF, a project made possible by the enduring collaboration of NMR aficionados from Cornell, Rochester, Buffalo and Syracuse.

The keynote speakers are Guy Montelione from Rutgers (day one) and Eaton Lattman from the Hauptman-Woodward Institute/SUNY Buffalo (day 2).

The program will start at 8 AM on October 19 and end at 5 PM on October 20, with breakfast and lunch provided on both days plus a reception on October 19 during which the poster session will take place. There is no registration fee for the entire event but we ask that you register so that we can plan ahead. We hope that everyone will be able to attend both days, regardless of the interest.



Poster Presenters: Poster size is 6ft (w) x 4ft (h)

NMR Conference - Monday, October 19


Keynote Presentation

Hybrid Approaches for Protein Structure Determination Combining Computational Modeling with Sparse NMR Restraints

Prof. Gaetano T. Montelione, Jerome and Lorraine Aresty Chair in Cancer Biology and Distinguished Professor, Center for Advanced Biotechnology and Medicine, Department of Molecular Biology and Biochemistry,  Rutgers University.

Structural Biology Symposium - Tuesday, October 20


Keynote Presentation

Biology with X-Ray Lasers

Prof. Eaton Lattman, BioXFEL Center & Department Structural Biology University at Buffalo, and CEO/Executive Director Emeritus at the Hauptman-Woodward Institute.



(as of September 10, 2015)

Monday, October 19, 2015 Gateway Center, SUNY-ESF, Syracuse, NY
14th Upstate NMR Symposium
8:00-9:00 AM Breakfast and Registration  
9:00 Welcome  

Session 1: "Probing Conformations & Dynamics by NMR"


“Linkage-specific conformational ensembles of non-canonical polyubiquitin chains from NMR and SANS studies”

Carlos Castañeda (Syracuse University)

“Using Overhauser-Effect DNP to Probe the Hydration Dynamics of Biological Systems”

John Franck (Cornell University)

“Insights into mechanisms of protein domain swapping”

Stewart Loh (SUNY Upstate)

10:15-10:25 Student Talk 1  
10:30-10:45 Coffee Break  
Session 2: "NMR of Small Molecules: Nucleotides and Metabolites"

“NMR of Small RNAs as Benchmarks for Force Fields”

Doug Turner (University of Rochester)

“13C-NMR Studies of Sterol Metabolism in Marine Invertebrates”

José Giner (SUNY-ESF)

“2D NMR-based comparative metabolomics: new structures from orphan genes”

Frank Schroeder (Cornell University)
12:00-12:10 PM Student Talk 2  
12:10-1:30 Lunch & Poster viewing  
Session 3: "Advances in NMR Techniques"

“Hybrid Approaches for Protein Structure Determination Combining Computational Modeling with Sparse NMR Restraints”

Guy Montelione (Rutgers University)

“NMR Methodology for Protein Studies”

Thomas Szyperski (SUNY Buffalo)


“Structural and energetic characterization of a repeat folding pathway using high pressure NMR”

Catherine Royer (RPI)
3:15-3:45 Coffee & Tour of the 800 Dave Kiemle (SUNY-ESF)

Session 4: “NMR of biological mechanisms


“Prolyl Isomerization and Alzheimer's Disease”

Linda Nicholson (Cornell University)

“Quinary protein interactions studied by in-cell NMR”

Alexander Shekhtman (SUNY Albany)

“Structural Mechanisms of Hedgehog Autoprocessing”

Chunyu Wang (RPI)
5:00-7:00 Reception & Poster Session  
Tuesday, October 20, 2015 Gateway Center, SUNY-ESF, Syracuse, NY
1st Upstate NY Structural Biology Symposium
8:00-9:00 AM Breakfast and Registration  
9:00 Welcome  
Session 1: "Membrane Protein Structure & Function"

Structure of the Transmembrane CaaX Protease STE24 Relating to its Role in Aging and Inhibition by Anti-Retroviral Drugs

Mark Dumont (University of Rochester)
9:25-9:45 "Ubiquitin and vesicle trafficking, how does bacterial pathogenexploit this ancient pathway?" Yuxin Mao (Cornell University)

“Global Redesign of a Native β-barrel Scaffold for Nanobiotechnology”

Liviu Movileanu (Syracuse University)
10:15-10:25 Student Talk 1  
10:30-10:45 Coffee Break  
Session 2: "Structure & Drug Discovery"

“Structure and Conformational Dynamics of the Essential Pre-mRNA Splicing Factor U2AF65”

Clara Kielkopf (University of Rochester)

“Grp94, the ER Hsp90: Add-ons Make the Chaperone”

Daniel Gewirth (HWI/SUNY Buffalo)

“Targeting the MLL1-WDR5 interface for inhibition of the Mixed Lineage Leukemia core complex”

Michael Cosgrove (SUNY Upstate)
12:00-12:10 PM Student Talk 2  
1:10-1:30 Lunch & Poster Viewing  
Session 3: "Emerging Technologies"

“Biology with X-ray Lasers”

Eaton Lattman (HWI/SUNY Buffalo)
2:30-2:50 TBA Rajendra Agrawal (Wadsworth Center)

“Using combined chemical crosslinking and mass spectrometry to understand the molecular architecture of macromolecular transcription complexes”

Bruce Knutson (SUNY Upstate)
3:20-3:30 Student Talk 3  
3:30-3:45 Coffee Break  
Session 4: "DNA/RNA Structure & Function"

“Translesion DNA Polymerases: Conformation is a Major Determinant of Fidelity and Specificity”

Janice Pata (Wadsworth Center)

“RNA-based immunity and gene regulatory mechanisms”

Ailong Ke (Cornell University)

“Structural Biophysics of Intrinsically Disordered Proteins”

Scott Showalter (Penn State University)
5:00 Program Ends -- Closing Remarks  


Lodging Information

The Hotel Skyler has agreed to provide a limited number of rooms at a discounted rate of $96.00 per night. When making your reservations please mention the Symposium organized by SUNY Upstate Medical University, Department of Biochemistry and Molecular Biology.

If you have issues with reservations or finding alternative locations contact Penny McPhilmy or Sandra Jarvis at the SUNY Upstate Medical University Biochemistry Department.

The Upstate NY NMR and Structural Biology Symposium is in part supported by generous contributions from the following sponsors:

    • Upstate Medical University
    • Syracuse University
    • SUNY-ESF
    • Bruker BioSpin
    • Cambridge Isotopes
    • New Era Enterprises, Inc.
    • Sigma-Aldrich Isotec
    • Shimadzu 


Katherina Searing
Associate Director, Professional Education and Non-credit Programs
ESF Outreach
Phone: 315-470-6888/6817
Fax: 315-470-6890