Chemistry at ESF
The Department of Chemistry at ESF is unique in that it is organized around the interdisciplinary areas of biochemistry and natural products chemistry, environmental chemistry and polymer chemistry.
We stress a strong foundation in the traditional areas of chemistry (analytical, inorganic, organic and physical chemistry) plus integration of these areas into its specialties. Students at all levels enjoy the advantages of a chemistry program with specialties aligned with the needs of the 21st century.
The department is committed to maintaining its leading role in extending the state of knowledge in its specialties. The department’s home is the 71,000-square-foot Edwin C. Jahn Laboratory. This state-of-the-art facility for research and teaching is well equipped with instruments needed for modern chemical research. The department involves all of its students in research, giving them familiarity with the actual practice of chemistry.
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Why ESF for Chemistry?
Featured Chemistry Paper
"Targeting the alternative sigma factor RpoN to combat virulence in Pseudomonas aeruginosa. "
Lloyd MG, Lundgren BR, Hall CW, Gagnon LB, Mah TF, Moffat JF, et al
- Read the paper (PDF)
The pathogen Pseudomonas aeruginosa continues to be an alarming threat to human health. Its resistance to antibiotics and its ability to thwart host-cell defense mechanisms make it a challenge to eradicate in infected individuals. To aid in the combat against this pathogen, our research group reported developing a small peptide we call the RpoN molecular roadblock (RpoN*). This peptide binds to bacterial DNA and blocks or prevents gene transcription. This inhibition resulted in decreased the ability of P. aeruginosa to produce a number of virulence factors: substances such as proteases and rhamnolipids that enhance the danger of this pathogen. In addition, RpoN* significantly reduced the rate of P. aeruginosa-mediated killing of a model system for its pathogenic behavior. These results highlight the feasibility of RpoN-mediated gene regulation in order to inhibit or reduce the virulence of bacterial human pathogens.
SUNY-ESF Chemistry Department
121 Edwin C. Jahn Laboratory
1 Forestry Drive
Syracuse, NY 13210-2726 USA
(315) 470-6856 (fax)