Arthur J. Stipanovic
123 Jahn Lab
1 Forestry Dr.
Syracuse, New York 13210
Dr. Arthur (Art) Stipanovic is currently Professor and Past Chairman of the Chemistry Department at SUNY-ESF where he received his B.S. and Ph.D. degrees. From 1998-2012, he was Director of the Analytical and Technical Service group at SUNY-ESF and, from 2010-2012, he served as Interim Co-Director of the CNY Biotechnology Accelerator, a business incubator located in Syracuse, NY. His research interests include biodegradable polymers from renewable resources, high-throughput analytical techniques for determining the composition of woody biomass and new pretreatment processes for the wood-based biorefinery.
Ph.D., 1979, SUNY-ESF, Polymer Chemistry
Dr. Stipanovic’s research group focuses on the use of renewable “woody” biomass for the production of fuels, chemicals and biodegradable materials. Specific program areas are highlighted below:
(1) Adaptation of “high-throughput” analytical techniques for the wood-based biorefinery including Near IR Spectroscopy, High-Resolution Thermogravimetric Analysis, analytical and process NMR. Emphasis on techniques that enable feedstock composition optimization for fast growing willow (Salix) species.
(2) Development of “commercially” implementable pretreatment technologies to reduce the inherent recalcitrance of woody biomass in a biorefinery such as High-Energy Electron Beam (EB) irradiation, biodelignification by white-rot fungi, and other environmentally “benign” pretreatments.
(3) Enhanced utilization of the “hemicellulose” fraction of woody biomass for biodegradable materials and composites. In collaboration with Professor Chris Nomura of SUNY-ESF, creation of a genetically engineered organism that will combine two functions: (1) utilization of xylose sugar from wood hemicellulose (vs. glucose sugar from corn) and, (2) the conversion of xylose directly into a biodegradable polyester useful for disposable consumer plastic applications.
(4) With Professor Stewart Loh of SUNY Upstate Medical University, evaluate synthetic “cellulosomes” from genetically engineered organisms which contain a soluble protein scaffolding onto which “cellulase” and “xylanase” enzymes, capable of converting woody biomass into fermentable sugars, are incorporated to enhance enzyme activity (sugar yield, conversion rate). Exploitation of “biomimicry” as a pathway to new enzyme functionalities.
(5) Development of a proprietary process to enhance the rate of glucose fermentation by yeasts to ethanol using EB treated hardwood extracts.
“Consolidated bioprocessing of poly(lactate-co-3-hydroxybutyrate) from xylan as a sole feedstock by genetically-engineered Escherichia coli”, Lucia Salamanca-Cordona, Christopher Nomura, Arthur J. Stipanovic, Journal of Bioscience and Bioengineering, Accepted March 2016.
“Integration of biomass pretreatment with fast pyrolysis: An evaluation of electron beam (EB) irradiation and hot-water extraction (HWE)”, Ofei D. Mante, Thomas E. Amidon, Arthur Stipanovic, Suresh P. Babu, Journal of Analytical and Applied Pyrolysis, 110, 44-54 (2014).
“Deletion of the pflA gene in Escherichia coli LS5218 and its effects on the production of polyhydroxyalkanoates using beechwood xylan as a feedstock”, Lucia Salamanca-Cardona, Ryan A Scheel, Benjamin R Lundgren, Arthur J Stipanovic, Ken’ichiro Matsumoto, Seiichi Taguchi, and Christopher T Nomura, Bioengineered 5:5, 1–4; September/October 2014
“Ionizing radiation and a wood-based biorefinery”, M.S. Driscoll. A.J. Stipanovic, K. Cheng, V.A. Barber, M. Manning, J.L. Smith and S. Sundar, Radiation Physics and Chemistry, 94, 217-220 (2014).
“Electron beam pretreatment of switchgrass to enhance enzymatic hydrolysis to produce sugars for biofuels”, S. Sundar, N.S. Bergey, L. Salamanca- Cardona, A.J. Stipanovic, and M. Driscoll, Carbohydrate Polymers, 100, 195-201 (2014).
“Enhanced production of polyhydroxyalkanoates (PHAs) from beechwood xylan by recombinant Escherichia coli”Lucia Salamanca-Cardona, Christopher S. Ashe, Arthur J. Stipanovic, Christopher T. Nomura* , Applied Microbiology and Biotechnology, 98, 831-842 (2014).
“Enzymatic Saccharification of Shrub Willow Genotypes with Differing Biomass Composition for Biofuel Production”, M.J. Serapiglia, M.C. Humiston, H. Xu, D.A. Hogsett, R.Mira de Orduna, A.J. Stipanovic, and L.B. Smart, Frontiers in Plant Biotechnology, 25 March 2013, 10.3389/fpls.2013.00057 (Published in Open access format online).
“Reducing Woody Biomass Recalcitrance by Electron Beams, Biodelignification and Hot-water Extraction”, Kun Cheng, Vincent A. Barber, Mark S. Driscoll, William T. Winter and Arthur J. Stipanovic*, Journal of Bioprocess Engineering and the Biorefinery, 2(2), 143-152 (2013).
Current Graduate Advisees
- Degree Sought: PHD
- Graduate Advisor(s): Stipanovic
- Area of Study: Polymer Chemistry
- Undergraduate Institute: Pennsylvania State University - University Park (Chemistry, General)